Procedure & Treatment Library

Pamidronate Infusion

What is a Pamidronate Infusion?

How is Pamidronate Administered?

What Are the Side Effects?

People commonly report flu-like symptoms and mild fever. This may occur when the Pamidronate is commenced and may last for approximately 48 hours.

Some people also report an increase in bone pain soon after commencing the Pamidronate.

Other possible side effects include pain and redness at the injection site, nausea, eye irritation, headache, tender or painful veins, and a rash affecting the hands, face, lips or throat. These side effects should reported to the nursing staff in hospital.

A rare side effect to Pamidronate is osteonecrosis of the jaw, which is a breakdown of the jaw bone. This is a very serious side effect and it is important that you advise your doctor if you notice any of the following:

It is best to avoid non-emergency dental procedures for 6 weeks after the infusion as dental surgery is thought to increase the rare risk of osteonecrosis happening.

It is recommended that you take calcium supplements for 1 month after each Pamidronate infusion as the infusion can occasionally lower the body’s calcium level in the bloodstream.

It is important that you advise your doctor of any other medications that you are taking prior to undergoing a Pamidronate infusion.

If you require further explanation of the procedure, please contact the nurses at Hunter Pain Clinic on (02) 4985 1800.

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