Ambroxol is a multifaceted drug with primarily mucoactive and secretolytic actions, along with anti-inflammatory, antioxidant, and local anaesthetic properties. In more recent years, ambroxol has gained interest for its potential usefulness in treating neuropathic pain.
This study aimed to evaluate the two-year effectiveness of this restorative neurostimulator in patients with disabling CLBP secondary to multifidus muscle dysfunction and no indications for spine surgery.
Neuromodulation. 2023; 26(1): 98-108.
Gabapentin is a recommended first-line agent for treating neuropathic pain; however, its efficacy rate is reportedly low, and the risk of adverse events is high. Pain Practice. 2023; 23(1): 63-69.
The aim of this article is to add to a framework started by IMMPACT for assessing the wider health impact of treatment with SCS for people with chronic pain, a ”holistic treatment response”.
Neuromodulation.
In this study, we found evidence of reduced levels of an important anti-inflammatory molecule known as interleukin-37 in CRPS patients, as well as involvement of the immune-activated Kynurenine pathway, which may be linked to pain in CRPS.
Journal of Neuroinflammation
Medical Hypotheses 119: 41-53
BMJ Case Reports
Pain Management 8(2): 79-83
Neuromodulation 21(1): 48-55
Neuromodulation 21(1): 38-47
Neuromodulation 21(1): 1-9
Breathe 13(4): 298-309
International Journal of Clinical Practice 71(9): e12961
Hospital Pharmacy 52(4)
Journal of Science and Medicine in Sport 20(S1): e15
Neuromodulation 20(1): 31-50
Neuromodulation 20(2): 133-154
Neuromodulation 20(2): 133-154
Journal of Clinical Gastroenterology
The American Journal of Sports Medicine 44(10): NP52-NP53
Journal of Opioid Management 12(3): 187-196
Pain Physician 19(4): 267-280
The European Journal of General Practice 30: 1-8
Neuromodulation 19(2): 179-187
Journal of Neuroimmunology 286: 77-78
Pain Practice 16(1): E14-20
Neuromodulation 18(5): 361-366.
The Journal of Pain 16(4): S67
Heart Rhythm 12(3): 588-595
Pain Medicine 16(5): 934-942
Neuromodulation 18(1): 50-57; discussion 57
Neuromodulation 18(1): 41-48; discussion 48-49
Neuromodulation 17(6): 515-550; discussion 550
Spine (Phila Pa 1976) 39(15): 1262
Neuromodulation
Neuromodulation 17(7): 656-664
Pain Practice 15(3): 208-216
Neuromodulation 16(5): 471-482; discussion 482
British Journal of General Practice 63(607): e149-155
Journal of International Medical Research 37(5): 1321-1335
Journal of Pain and Symptom Management 37(3): e9-10
Australian Doctor 21(March): 25-32
European Journal of Pain Supplements 1(1): 74-77
Pain 122(1-2): 216; author reply 216
Anaesthesia and Intensive Care 34(1): 127; author reply 127
Pain Practice 5(4): 367
Anaesthesia and Intensive Care 32(1): 145-146
Anesthesiology 87(4): 1010-1011; Author Reply 1013-1014
Complex regional pain syndrome (CRPS) is a debilitating condition where trauma to a limb results in devastating persistent pain that is disproportionate to the initial injury.
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